In recent decades, a variety of pharmaceutical research has been conducted to develop new dosage forms. The desire of improved palatability in orally administered products has prompted the development of numerous formulations with improved performance and acceptability. Mouth dissolving tablets (MDTs) have received ever-increasing demand during the last few decades and the field has become a rapidly growing area in the pharmaceutical industry. The unique property of mouth dissolving tablet is that they are rapidly disintegrating or dissolving and release the drug as soon as they come in contact with saliva, thus obviate the requirement of water during administration. Such formulations provide an opportunity for product line extension in the many elderly persons will have difficulties in taking conventional oral dosage forms (viz., solutions, suspensions, tablets and capsules) because of hand tremors and dysphagia. Swallowing problems also are common in young individuals because of their underdeveloped muscular and nervous systems. Other groups that may experience problems using conventional oral dosage forms include the mentally ill, the developmentally disabled and patients who are uncooperative, on reduced liquid-intake plans, or are nauseated. In some cases such as motion sickness, sudden episodes of allergic attack or coughing and an unavailability of water, swallowing conventional tablets may be difficult. This review also provides the detailed concept of some unique patents, technologies developed and marketed formulations of mouth dissolving tablets (MDTs).
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